Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease

Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality from PubMed:

Associations of dietary cholesterol or egg consumption with incident cardiovascular disease and mortality importance cholesterol is a common nutrient in the human diet and eggs are a major source of dietary cholesterol whether dietary cholesterol or a consumption is associated with cardiovascular disease cvd and mortality remains controversial objective to

Determine the association’s of dietary cholesterol or egg consumption with incident cvd and all cause mortality design setting and participants individual participant data were pooled from six perspective us cohorts using data collected between march 25th 1985 and august 31st 2016 self-reported diet data were harmonized using the standardized protocol exposures

Dietary cholesterol mg day or a consumption number day main outcomes and measures hazard ratio hr and absolute risk difference ard over the entire follow up for incident cvd composite of fatal and non-fatal coronary heart disease stroke heart failure and other cvd deaths and all cause mortality adjusting for demographic socio-economic and behavioral factors

Results this analysis included 29 615 participants mean sd age fifty one point six thirteen point five years at baseline of um thirteen 299 44.9% were men in nine thousand two hundred and four thirty one point one percent were black during a median follow-up of seventeen point five years interquartile range 13.00 no one point seven maximum 31.3 there were 5,400

Incident cvd events and six thousand one hundred thirty-two all caused deaths the association’s of dietary cholesterol or a consumption with incident cvd and all cause mortality were monotonic all p-values for nonlinear terms dot one nine eight three each additional three hundred milligrams of dietary cholesterol consumed per day was significantly associated with

Higher risk of incident cvd adjusted a charm 1.17 95% ci 1.0 91.26 adjusted arb three point two four percent 95 percent ci 1.3 nine percent – 5.0 eight percent and all cause mortality adjusted hr one point one eight 95% ci 1.10 one point two six adjusted ard four point four three percent 95 percent ci 2.5 1% – 6.3 six percent each additional half and a consumed per

Day was significantly associated with higher risk of an incident cvd adjusted bank charm one point zero six 95% ci one point zero three 1.10 a just a day rd one point one one percent ninety-five percent ci 3 – % – 1.8 9% and all cause mortality adjusted hr 1.08 95% ci 1.0 for 1.11 adjusted ard 1.9 3% 95% ci 1.1 0% – 2.7 6% the associations between a consumption

And incident cvd adjusted hr 0.99 95% ci 0.93 1.05 adjusted ard – point 4 7% 95% ci minus 1.8 3% two point eight eight percent and they’ll cause mortality adjusted hr one point zero three 95% ci point nine seven one point zero nine adjusted ard 0.71% 95% ci minus 0.85 percent to two point two eight percent were no longer significant after adjusting for dietary

Cholesterol consumption conclusions and relevance among us adults higher consumption of dietary cholesterol or eggs was significantly associated with higher risk of incident cvd and all cause mortality in a dose-response manner these results should be considered in the development of dietary guidelines and updates

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Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease – PubMed By JY Health