Thyroid and Anti-Thyroid Medications – Pharmacology (Pharm) – Endocrine System – Level Up RN

The indications, mode of action, side effects, and key points associated with the following thyroid and anti-thyroid medications: levothyroxine, liothyronine, propylthiouracil (PTU), and strong iodine solution (Lugol’s solution).

Video, i’m going to continue my coverage of   endocrine system medications. specifically, i’ll  be covering thyroid and anti-thyroid medications.   if you have our level up rn pharmacology second  edition flashcards, definitely pull those out and   follow along with me. at the end of the video,  i’m going to provide a quick quiz for

You guys   to test your understanding of some of the key  facts and concepts that i’ll be covering in   so let’s start by talking about our thyroid   medications which include levothyroxine as well as  liothyronine. so these medications really act as a   synthetic form of our naturally occurring thyroid  hormones, and we

Would use them in the treatment   of hypothyroidism. so side effects are minimal  unless the dose is too high. in that case, we may   end up with signs and symptoms of hyperthyroidism.  so signs and symptoms can include anxiety, gi   upset, sweating, weight loss, and heat intolerance  if the patient has hyperthyroidism. there’s

Also   a black box warning with this medication class  to warn people that thyroid hormones are not   to be used for the treatment of obesity or to help  the patient lose weight. in terms of the dosing,   patient’s tsh and t4 levels, and, periodically,   we may need to increase or decrease their dose  according to

Whatever those tsh and t4 levels are.  lifelong treatment is required with these thyroid   medications, so it’s not like they’re going to  take levothyroxine for a little while and suddenly   their thyroid gland is going to produce sufficient  t3 and t4. that’s not going to be the case,   so they’re going to need to take this

For the rest  of their lives. the dose may need to be adjusted   at times, but it will be lifelong treatment. in  terms of administration, we want to counsel the   patient that they should take this medication on  an empty stomach with a full glass of water before   medications with a full glass of water well before  the

Breakfast trays are delivered to the floor. so   in terms of how i remember that these medications  are used to boost up the thyroid hormone levels,   or liothyronine, they both have that thyro,   remember that these medications are used   all right. now, we’re going to talk about   different medications i’m going to talk

About.   is used in the treatment of grave’s disease,   which is a key cause of hyperthyroidism. it is  also used in preparation for a thyroidectomy.   so ptu works by blocking the synthesis of thyroid  hormones, so it helps to bring those levels down.   which is a decrease in granulocytes,  so with this side effect,

It does place the  patient at increased risk for infection.   well as hepatotoxicity, which is a black box   warning for this medication class. also, if the  patient’s dose of ptu is too high, it can cause   this includes symptoms such as lethargy,   weight gain, cold intolerance, bradycardia, and  depression. so as

The nurse, when a patient is on   ptu, you want to monitor their cbc levels because  of that side effect of agranulocytosis. and we’re   also going to want to monitor their liver function  because of that side effect of hepatotoxicity.   so the way i remember this medication and what  it’s for when i look at p-t-u, i think of

Prevents   thyroid for being up too high, and that’s exactly  what it does. it prevents those thyroid levels   another anti-thyroid medication to know is   something called lugol’s solution, which is a  strong iodine solution. so this is a combination   of iodine and potassium iodide, and it is used  in the treatment of

Hyperthyroidism as well as   hyperthyroidism that’s life-threatening.   thyroidectomy. so lugol’s solution is absorbed   by the thyroid gland, and there it inhibits the  production and release of thyroid hormones. side   and iodism. so signs and symptoms of iodism   is inflammation of the mucosa in the mouth  

This medication tastes really bad, apparently.   understanding. so you can mix it with a lot of   okay. time for a quiz. question number 1.   levothyroxine should be given once a day with  food. true or false? the answer is false. it   should be given without food and a full glass  of water before breakfast. so remember,

We wake   them this medication with a full glass of water.  medication carries the risk for iodism?   question number 3. if a patient’s dose of ptu  – so that’s propylthiouracil – is too high,   is hypothyroidism. so remember, ptu prevents   the thyroid from being up too high, so it reduces  those thyroid levels. so

If we do that too much,   okay. i hope these quiz questions have been   helpful. hopefully, the video helped as well.  if you got any of these questions wrong,   replay the video. i know you’ve got this,   so take care and good luck studying. i invite you  to subscribe to our channel and share a link with   your

Classmates and friends in nursing school.  if you found value in this video, be sure to   hit the like button and leave us a comment and  let us know what you found particularly helpful.

Transcribed from video
Thyroid and Anti-Thyroid Medications – Pharmacology (Pharm) – Endocrine System – @Level Up RN By Level Up RN