Xidolac Meltab

Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) chemically related to indomethacin and tolmetin. Ketorolac tromethamine is a racemic mixture of [-]S- and [+]R-enantiomeric forms, with the S-form having analgesic activity. Its antiinflammatory effects are believed to be due to inhibition of both cylooxygenase-1 (COX-1) and cylooxygenase-2 (COX-2) which leads to the inhibition of prostaglandin synthesis leading to decreased formation of precursors of prostaglandins and thromboxanes from arachidonic acid. The resultant reduction in prostaglandin synthesis and activity may be at least partially responsible for many of the adverse, as well as the therapeutic, effects of these medications. Analgesia is probably produced via a peripheral action in which blockade of pain impulse generation results from decreased prostaglandin activity. However, inhibition of the synthesis or actions of other substances that sensitize pain receptors to mechanical or chemical stimulation may also contribute to the analgesic effect. In terms of the ophthalmic applications of ketorolac – ocular administration of ketorolac reduces prostaglandin E2 levels in aqueous humor, secondary to inhibition of prostaglandin biosynthesis.

Foreign pharmaceuticals limited bangladesh product overview trade name civil act mail tab generic name ketoelectromethamine production company beximco pharmaceuticals limited bangladesh category anal g6 antipyretic price per unit 10 tarkas commercial pack box containing 20 tablets in alu alu form packs each mouth dissolving tablet contains ketoelectromethamine

Usp 10 milligrams what is citalac melt app citalac meltab and mouth dissolving tablet contains ketoelectromethamine usp 10 milligrams ketoelectromethamine is a drug of pyrolopyrol group of non-steroidal anti-inflammatory drug nsaid it inhibits synthesis of prostaglandin and may be considered as a peripherally acting analgesic the biological activity of

Ketoelectromethamine is associated with the s form icore kinetic property of ketoelectromethamine is linear it is highly protein bound and is largely metabolized in liver the products of metabolism and some unchanged drugs are excreted in the urine indications ketoelectromethamine is indicated for the short-term management of moderate to moderately severe acute

Pain that requires analgesia at the opioid level usually in a post-operative setting dosage and administration by mouth 10 milligrams every four to six hours elderly every six to eight hours or maximum 40 milligrams daily maximum duration of treatment is seven days side effects it is generally well tolerated however side effects like gastrointestinal disturbances

Including gastrointestinal bleeding perforation and peptic ulceration other side effects reported include anaphylaxis rash bronchospasm dry mouth excessive thirst psychotic reactions convulsion myalgia hyponatremia hyperkalemia raised blood urea and creatinine renal failure hypertension bradycardia chest pain for pera post-operative hemorrhage hematoma liver

Function changes etc may occur contraindications ketoelectromethamine is contraindicated in patients with known hypersensitivity to nsa ids and any of the components to ketoelectromethamine moreover the patient with the history of asthma nasal polyp angioedema peptic ulcer and bleeding disorder are contraindicated for this drug precautions should be taken in the

Following conditions elderly allergic disorder renal cardiac and hepatic impairment porphyria patient with low body weight less than 50 kilograms reduced dose use in pregnancy and lactation ketoelectromethamine is contraindicated in pregnancy and lactation use in children not recommended for children below 16 years of age drug interactions ketoelectromethamine

Should not be given to patients already receiving anticoagulants or to those who will require prophylactic anticoagulant therapy including low-dose heparin the risk of ketorolac associated bleeding is also increased by other nsaids or aspirin and bipentoxicillin and use together should be avoided proven acid increases the half-life and plasma concentrations of

Keto rolex and the two drugs should not be given together overdosage overdosage of ketoelectromethamine may cause abdominal pain pepticulses which healed after discontinuation of dose metabolic acidosis has been reported following over dosage pharmaceutical precautions keep in a cool and dry place protect from light keep out of the reach of children

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Xidolac Meltab By Cristal Glass